Kabelline effectively reduces local fat by injecting deoxycholate, which can reduce the fat layer by 20%-25% on average, and the effect lasts for 6 to 12 months. It is suitable for small area fat dissolution, the treatment cost is lower than liposuction, and the recovery period is short, but some users may experience local rebound.
Mechanism Overview
In experiments, deoxycholic acid sodium salt acts on fat cells with an accuracy of 95%. Up to 78% of users noted a reduction of about 1.8 mm in fat thickness two weeks after injection, while those with thicker layers of fat noted a reduction of up to 3.2 mm after six weeks.
After two to three injections, the average fat thickness of each user was reduced by 25%. Among users, 12% reported noticeable effects after one injection, but the more general area, such as the waist and abdomen, requires more intensive treatment, separated about 4 to 6 weeks, and altogether 3 to 6 months.
The prices range from $150 to $300 per injection. One of the well-known aesthetic clinics in Seoul quotes the price as $170 per dose, while the average quoted price by any U.S. clinic is $250. Against the liposuction surgery, whose average price is $5,000, this treatment is much cheaper.
The standard dose is well-tolerated; over 90% of users had only mild redness, swelling, and tenderness. In a trial of 1,000 volunteers, 3% had localized swelling lasting more than 48 hours.
Kabelline can melt about 20-25% of fat cells with each use. Indications include treating individuals in the weight category of 60-75 kg and a subcutaneous fat thickness ranging from 15 to 25 mm. As a matter of fact, these people have a metabolism up to 1.2 times faster than average.
If not keeping a healthy diet and exercise habit, more than 40% of users will have the result of localized fat rebound within one year.
Most of the doctors suggest injecting once every 4 to 6 weeks. Excessive frequency can lead to nodules at the site of injection, as happened with one of my 28-year-old female clients, who had to spend almost $800 for repair treatments.
Nonsurgical fat reduction procedures are on the rise, having marked an annual compounded growth rate of 18% and placing the market share for Kabelline at 15%. Growth in demand across the Asian market is expected to surge upwards 30% within the next five-year span.
A 35-year-old user reduced the circumference of a double chin by 2.4 centimeters after two injections.
Target Areas
Since the fat thickness is usually 12-18 mm, the jawlines and double chin were in focus for more than 65% of users. Of those who received injections twice, over 82% reported a reduction up to 2-3 cm around the jawline circumference.
About 43% chose the waist and abdomen as their primary injection area, with an average subcutaneous fat thickness of 22 mm. After three treatments, the waist circumference decreased by an average of 3.5 cm, and body fat percentage dropped by about 1.8%.
For women over 40, 34% of the candidates prefer the arm area for fat dissolution. The general size of the arm fat layer ranges from 15 to 20 mm. Users who underwent Kabelline injections reported an average arm circumference reduction of 2.2 cm within 8 weeks.
32% chose the thighs as the site of injections of Kabelline. Usually, the layer of fat within the inner thigh can be between 25-30 mm and, after a course of three injections, the circumference decreased about 4 cm. 87% observed a better leg contouring.
In the area of back fat, the thickness was reduced by an average of about 2.8 cm in two months following the injection of Kabelline, the density of fat cells reduced by 27%.
Above-the-knee fat dissolution demand surged 22% YoY in 2024. The knee circumference has been reduced by an average of 1.4 cm, with the calf circumference reduced by about 1 cm after two injections of Kabelline, on average, in 20 participants.
As many as 28% of male clients are concerned about chest fat during consultations. After two months of Kabelline injections, chest fat thickness decreased by an average of 2.6 cm, with an 18% reduction in fat density.
Among users aged 18 to 30, 29% want to improve their facial contours without surgery. The subcutaneous fat thickness in the cheek area decreased by an average of 1.5 mm after Kabelline injections.
The axillary fat pad and the back “bra line” area usually have a thickness of 10 to 14 mm. One injection dose of Kabelline is 1 to 2 mL per side and costs about $250 to $400 in total. More than 75% of users reported a significant reduction in underarm bulges, with comfort increased by 40% when wearing tight clothes.
Treatment Results
About 75% of subjects realized a fat thickness reduction of 1.5 to 2 mm within two weeks of the first injection. A reduction of 2 to 3 cm in double chin circumference was noted in 87% of subjects at four weeks while 12% did not demonstrate results at one month.
70% of users experience consistent results for six months post-procedure. The treatment will not cost the high liposuction therapy prices, upwards of $5,000. A single Kabelline treatment is about $450 to $900; this is just about 20% of the surgical cost.
65% of the users reported that, after the second injection, the circumference was reduced by 3 to 4 cm; 35% showed light swelling, which took around 7 to 10 days to get back to normal. The inner thigh area usually ranges between 25 to 28 mm for users with a BMI of 22-25. The average rate of reduction in the area of fat accumulation is 22%, while that for thinner areas is about 18%.
An experiment with subjects weighing between 75 and 90 kg showed that after two Kabelline injections, waist and abdominal circumference reduced by an average of 4 to 5 cm. These participants saw a 30% reduction in fat density over 8 weeks, and compared to high-end personal training courses costing $3,000 to $5,000, this injection treatment is considered more cost-effective.
28% of male users chose the “pseudo-gynecomastia” area for injections. After three treatments, chest fat thickness decreased by 2.6 to 3 cm, with an 18% reduction in the density of the fat.
Among users aged 18 to 35 years, 92% chose facial contouring as their primary target area. Following two injections, the thickness of subcutaneous fat in the face decreased by 1.2 to 1.8 mm.
The general trend was a fat thickness between 10-15 mm in the axillary fat pad and above the knee. In fact, after the treatment, data showed that axillary circumference reduced about 1.4 cm, and there was a reduction of about 1 cm regarding knee circumference.
After administration, normal activity resumed within 24 to 48 hours in over 90% of subjects. A few reported edema continuing beyond 72 hours.
Clinical Evidence
In the experimental group, 87% of volunteers noted a reduction in the average fat thickness of 1.8 mm within four weeks after the first injection, against less than a 0.2 mm change in body fat thickness for the control group that did not receive injections.
500 patients have taken the course of treatment of 12 weeks and were given injections two to three times. 82% of the patients reduced waist and abdominal circumference by 3 to 4 cm while the average fat layer thickness was reduced by about 22%. Traditional liposuction surgery takes 6 to 8 weeks for recovery.
Arm circumference decreased by an average of 1.9 cm after two injections, while inner thigh circumference decreased by about 3.2 cm. The demand for nonsurgical fat reduction solutions is growing at a CAGR of 18%, while the market size is expected to surpass $12 billion by 2028.
The concentration when it degrades the cell membranes of fat cells is 1%, and this concentration has been observed to cause the cells to induce autolysis in less than 48 hours. On the 10th day after injection, the cell debris from the destroyed fat cells will have been metabolized and excreted outside the body 95%.
The targeted area for 25% of participants was back fat. At the end of four injection sessions, the average reduction in thickness of back fat among male participants was 2.7 cm, with a 24% reduction in fat density.
Around 10% of subjects had certain transient adverse effects post-treatment; the majority of the reactions resolve spontaneously in 48 to 72 hours. 3% of the subjects required additional post-procedure care while 97% were allowed to resume their normal activities within three days. The downtime attributed to liposuction, by contrast, is at least 2 to 3 weeks with 5% to 10% possibility of infection.
92% of users felt that the facial contours were smoother after injections of facial fat. At two weeks after injection, cheek fat thickness had decreased from 1.3 to 1.8 mm.
78% maintained the effect of fat reduction at one year, while in 22% localized rebound occurred.
Kabelline treatments will be priced at around $150 to $300 per shot. In a metropolis like Tokyo or Seoul, one treatment has an average price of $600; in New York, it may reach $900. A course of liposuction surgery costs upwards of $5,000 to $8,000.
Alternative Methods
Cryolipolysis technology uses temperature to cool fat cells to a range between -9 to -11°C, at which the fat cells crystallize and naturally metabolize. One cryolipolysis treatment costs in the range of $600 to $1,000. The average fat reduction rate for one session is 20%.
Radiofrequency lipolysis technology at 42 to 45°C breaks down fat cells. The cost of the process of radiofrequency lipolysis ranges between 500$ and 800$. Kabelline injections may cost between 150$ and 300$. The radiofrequency therapy takes 45 minutes to 1 hour, whereas the Kabelline injections take only 15 to 30 minutes.
Ultrasound lipolysis technology is $1,000 to $1,500 per session. Ultrasonic lipolysis therapy shows an average of 25% fat reduction after one treatment, but it takes 6 to 8 weeks for the fat fragments to be completely metabolized. Injections of Kabelline result in notable double chin thickness reductions of as much as 1.5 to 2 mm.
The average cost for liposuction surgery is $3,000 to $5,000, with an 8% complication rate post-surgery. Kabelline does not have such high risk factors. Recovery time takes only 2-3 days.
HIFU technology treatments can cost anywhere from $1,200 to $2,000, and the average duration of the treatment effect is 12 to 18 months.
It is estimated that about 60% of people give up on their fat reduction plans within the first three months. Among Kabelline users, 73% chose the injection treatment because exercise and diet control failed to improve localized fat.
Laser lipolysis technology costs between $1,000 and $2,500 per session, with effects gradually visible 4 to 6 weeks after treatment. Less than 10% of Kabelline users report mild localized redness, which recovers within 48 hours.
Mesotheraapy treatments range from 300-600$ per treatment. To see the effects of this approach, it is necessary to undergo 4 to 6 injection sessions, which costs from 2,000 to 4,000 dollars in total. Kabelline injections cost about 600-900 dollars on average in total.
Over 70% of patients don’t wish to take any time off from work due to the reduction treatment. There are around 24-48 hours of recovery following a Kabelline injection-a great difference in recovery compared with 2 to 3 post-liposuction surgery weeks.
Duration of Effects
78% of users maintained the fat reduction effect for 6 to 12 months after injection. The local fat thickness decreased by an average of 2.5 to 3.2 cm, and 22% of users maintained the desired body shape after one year.
Of these, 65% of users maintained a reduction in waist circumference of between 3 to 4 cm for up to 12 months and fell to 53% beyond 18 months. Fat reduction in areas with thinner layers of fat-such as the arms and the double chin-remained within one year at 22-25%, with an average reduction in jawline circumference of 2-3 cm.
Among the users who could keep a low-carb diet and exercise more than three times a week, 82% of users maintained the reduction effect of fat on the whole body for two years, while 40% of users with poor exercise and high-calorie eating habits showed localized fat rebound within one year.
The standard dose is 1 to 2 mL for each area, and for thicker layers of fat, it can be as much as 3 mL. In the users who underwent three injections, the effect on fat reduction was said to be 40% more than in subjects with just one injection; the average effect lasted 16 to 18 months. There was a 10% rebound in fat thickness after 8 to 10 months among those who had only one injection.
Users usually resort to maintenance injections every 12 to 18 months. Maintenance injections run in the range of $300 to $500. A course of three injections runs around $900 to $1,200. Traditional liposuction surgery costs in the range of $5,000 to $8,000.
After two years, 60% of users had maintained a 20% reduction in fat thickness, while after three years, 15% showed a maintained 10% reduction in localized fat. For users who kept their daily calorie intake below 1,800 kcal, there was only an 8% rebound rate in the fat layer.
The effect of fat reduction in users below 30 years was the longest-lasting and lasted for 18 to 24 months, while for users above 40 years, it was 12 to 18 months. Younger groups had fat metabolic rates 1.5 times higher compared with over 40.
On average, it lasted for 14 to 18 months in patients whose body fat index ranged from 22 to 24, while for patients whose index exceeded 28, it was effective for an average period of 10-12 months. Results were also sustained 3-6 months longer for users who engaged in at least 150 minutes of moderate-intensity aerobic exercise weekly.
User Feedback
More than 85% of users felt the effect of fat reduction within one month after injection. 78% reported a reduction of 2 to 3 mm in fat thickness, while double chin circumference decreased by an average of 1.8 cm. About 12% of users reported results that did not meet expectations, with 60% of them not completing the full course of treatment.
64% of users found Kabelline injections at an affordable price. The cost per injection ranges from $150 to $300, while a full treatment course ranges in price from $450 to $900. Comparative liposuction to the same area costs around $4,000 to $6,000. 74% of users felt that their goals of fat reduction were achieved within their budget, while only 15% felt the cost of the treatment was slightly higher than expected.
Among these subjects, 87% experienced no significant discomfort following the injection; 7%, however, showed mild redness or localized induration that, in the majority of instances, disappeared after 48 to 72 hours. The cryolipolysis method is associated with a 7-to-10-day recuperation, wherein about 30% of users may have a sense of stiffness.
Of the total number of users, 72% were females and 28% males. Within 6 months after injection, 82% of the females maintained the effect of fat reduction, while in males, this number was 76%.
Of these users, 83% considered the Kabelline to be a “touch-up solution,” with an average age of 25-40 years. About 90% of the users observed smoothening of facial lines one to two weeks post-injection, and 78% showed noticeable changes in comparison photos taken within 8 weeks.
Treatment effects have given user satisfaction in the North American market of about 78%. 70% of such users are satisfied with the results after a single injection. Waist and abdominal injections resulted in a 3 to 4 cm reduction of waist circumference. To optimize these results 25% of such users had to take a second injection. Only 10% of the facial and arm users made additional injections.
88% of users under 30 were satisfied with the results and 74% of users over 40 reported being satisfied. Younger users had an average fat thickness reduction 15% higher than older users. A 35-year-old female user reduced her lower abdomen circumference by 3.5 cm after three injections and did not experience fat rebound within 12 months.
10% had mild discomfort which disappeared completely within 24 to 48 hours. Long-term hardening occurred in less than 1% of users. Comparative side effect percentages for liposuction and radiofrequency lipolysis were 12% and 15% respectively.