effectiveness, both can effectively remove wrinkles, but American botulinum toxin has a longer duration (about 5–6 months) while Korean lasts 3–4 months. In terms of price, cost-conscious patients tend to choose Korean , which costs only 2–5 USD per unit, far lower than the American’s 10–15 USD per unit.
Composition Differences
The molecular weight of Korean botulinum toxin is usually around 150 kilodaltons, while the molecular weight of ordinary botulinum toxin fluctuates between 140 and 180 kilodaltons. Research shows that the error margin in delicate facial areas for Korean botulinum toxin is below 5%, while that for ordinary botulinum toxin is about 10%.
Each unit of Korean botulinum toxin has a price between 2 and 5 USD, while ordinary botulinum toxin has a price between 10 and 15 USD. If one treatment requires 30 units, the cost of using Korean botulinum toxin is approximately 60 to 150 USD, whereas ordinary botulinum toxin costs 300 to 450 USD.
According to data, among patients using Korean botulinum toxin, only 0.5% experience mild allergic reactions, whereas this proportion is 2% among users of ordinary botulinum toxin. The effect of ordinary botulinum toxin usually lasts 5 to 6 months, while that of Korean botulinum toxin lasts 3 to 4 months. A survey of 800 patients showed that 72% of patients using Korean botulinum toxin needed a follow-up visit within 3 months, while only 40% of ordinary botulinum toxin users required a follow-up within the same period.
Patients can see initial effects 2 to 3 days after receiving an injection of Korean botulinum toxin, whereas ordinary botulinum toxin takes 5 to 7 days. Korean botulinum toxin occupies nearly 50% of the Asian market, while ordinary botulinum toxin holds nearly 70% of the global market.
The production and approval cycle for Korean botulinum toxin is usually completed within 3 to 5 years, while the approval cycle for ordinary botulinum toxin may take up to 10 years. Statistics show that 75% of Korean botulinum toxin users choose it for facial aesthetics, whereas ordinary botulinum toxin accounts for up to 40% of medical uses.
Cost Effectiveness
According to market statistics, the unit price of Korean botulinum toxin is approximately 2 to 5 USD, while the price of ordinary botulinum toxin is usually 10 to 15 USD. If one treatment requires 30 units, the total cost of using Korean botulinum toxin is between 60 and 150 USD, whereas ordinary botulinum toxin may cost as much as 300 to 450 USD.
Data show that in the Asian market, sales of Korean botulinum toxin account for 48% of the overall botulinum toxin market, with a compound annual growth rate of 12%. The effect of Korean botulinum toxin typically lasts 3 to 4 months, while ordinary botulinum toxin can last 5 to 6 months. On an annual basis, using Korean botulinum toxin requires 3 to 4 treatments, with a total cost of about 180 to 600 USD; whereas using ordinary botulinum toxin requires only 2 treatments, with a total cost of 600 to 900 USD.
Research shows that 80% of consumers believe that Korean botulinum toxin performs better than ordinary botulinum toxin around the eyes and mouth corners. Ordinary botulinum toxin requires 10 years of research and development and approval cycles, while Korean botulinum toxin can be brought to market within 3 to 5 years. According to data from the Korean Biopharmaceutical Association, the research and development costs for Korean companies are about 40% lower than those of European and American brands.
A survey covering 1000 users found that 70% of consumers believe that the short-term price and effect of Korean botulinum toxin outperform ordinary botulinum toxin, especially given the injection response that shows a rapid effect 2 to 3 days after administration. Ordinary botulinum toxin typically takes 5 to 7 days to show effects.
In the domestic Korean selling market, the botulinum toxin treatment price is about 25% lower than in the overseas market. For example, locally in Korea, the cost for a 30-unit botulinum toxin treatment averages 50 USD, while in overseas markets, the price can reach 75 USD. Statistics show that the brand premium for ordinary botulinum toxin is nearly 30%, whereas the brand premium for Korean botulinum toxin usually does not exceed 10%.
Purity Levels
According to data, the purity of ordinary botulinum toxin usually reaches above 99.5%, while the purity of Korean botulinum toxin generally ranges from 98.0% to 99.2%. The higher purity of ordinary botulinum toxin reduces the risk of drug resistance, with an antibody formation probability of less than 1%, whereas that for Korean botulinum toxin is 2%.
Ordinary botulinum toxin controls residual impurities at below 0.05%, whereas the level of residual impurities in Korean botulinum toxin is usually between 0.1% and 0.2%. The concentration of active protein in ordinary botulinum toxin is typically above 95%, while that in Korean botulinum toxin fluctuates between 90% and 93%. A clinical study involving 500 patients showed that the average duration of efficacy for ordinary botulinum toxin is 5 to 6 months, whereas that for Korean botulinum toxin is 3 to 4 months.
Korean manufacturers have reduced the non-active protein content by 30% through improved production processes. According to market data, among the newly launched Korean botulinum toxin products in 2023, over 50% have non-active protein content below 5 nanograms, while some low-end brands exceed 10 nanograms in non-active protein content.
Ordinary botulinum toxin is unit-priced at 10 to 15 USD, while Korean botulinum toxin is priced at 2 to 5 USD. A survey in 2023 showed that over 60% of consumers consider the price advantage as the main factor when choosing Korean botulinum toxin.
Research indicates that over 90% of patients using ordinary botulinum toxin achieve the expected results within 10 days after injection, while the achievement rate for Korean botulinum toxin is 80%. The diffusion error for ordinary botulinum toxin is controlled within 5%, whereas the diffusion error for Korean botulinum toxin can reach 10%.
A questionnaire survey covering 1000 consumers showed that the user satisfaction score for ordinary botulinum toxin averages 8.5 out of 10, while that for Korean botulinum toxin is 8.1. Data indicate that in 2022, over 70% of Korean botulinum toxin products exported were concentrated in the Asian market, while the demand for high-purity botulinum toxin in the European and American markets accounted for as much as 80%.
Multiple clinical studies show that the immune rejection rate for ordinary botulinum toxin is below 0.5%, whereas that for Korean botulinum toxin is around 1%.
Safety Data
According to clinical data from 2000 users, the allergic reaction rate for ordinary botulinum toxin is 0.4%, while Korean botulinum toxin shows an allergic reaction rate of 1%. The purification efficiency of some low-end Korean botulinum toxin products falls below 95%, and one brand reports a protein impurity residue of 8 nanograms, while ordinary botulinum toxin usually remains below 5 nanograms; a 2023 study finds that 8% of Korean botulinum toxin users report local discomfort, compared to only 3% among ordinary botulinum toxin users.
normally exhibits a diffusion error within 10%, whereas Korean botulinum toxin may reach a diffusion error of 15%. A study covering 500 patients shows that when treating fine facial areas such as crow’s feet, ordinary botulinum toxin attains a precision rate of 90%, while Korean botulinum toxin achieves a precision rate of 80%.
Data indicate that Korean botulinum toxin typically shows an onset time of 2 to 3 days, while ordinary botulinum toxin requires 5 to 7 days; one international brand completes a multi-stage clinical trial over 10 years before market entry, whereas Korean botulinum toxin usually completes approval within 3 to 5 years. onset trial market approval time
Market complaint data for Korean botulinum toxin show that there are 6 safety problem complaints per 1,000 doses, while ordinary botulinum toxin records only 3; a retrospective survey involving 200 users finds that 12% of Korean botulinum toxin users report local redness and swelling within 24 hours post-injection, compared to 7% among ordinary botulinum toxin users.
Korean botulinum toxin costs 2 to 5 USD per unit, while ordinary botulinum toxin costs 10 to 15 USD; data from 2022 reveal that in cases of safety issues due to injections with low-quality botulinum toxin, 60% involve uncertified Korean brands, compared to 20% for ordinary botulinum toxin.
Ordinary botulinum toxin produces an immune tolerance formation probability of less than 0.5% after long-term use, while Korean botulinum toxin shows a rate of 1%; a study of 100 long-term users shows that among patients who receive more than 10 injections of ordinary botulinum toxin only 1 reports drug resistance, while 3 cases of resistance appear with Korean botulinum toxin.
Results Longevity
Ordinary botulinum toxin typically maintains its effect for 5 to 6 months, while Korean botulinum toxin usually lasts 3 to 4 months; a clinical study covering 800 patients indicates that 85% of ordinary botulinum toxin users remain satisfied within 6 months after treatment, whereas the satisfaction rate for Korean botulinum toxin drops to 65 after 3 months.
The molecular weight of ordinary botulinum toxin generally concentrates between 140 and 150 kilodaltons, while Korean botulinum toxin ranges from 120 to 160 kilodaltons.
A consumer survey shows that among users who receive injections for more than 2 consecutive years, ordinary botulinum toxin users attend follow-up visits twice a year, whereas Korean botulinum toxin users attend follow-ups 3 to 4 times annually; calculating the average treatment cost per session, ordinary botulinum toxin costs between 600 and 1000 USD per year, while Korean botulinum toxin costs between 400 and 1200 USD annually.
Ordinary botulinum toxin typically has an active protein concentration above 95%, while Korean botulinum toxin ranges from 90% to 93%; ordinary botulinum toxin shows a 15% probability of diminished activity within 28 days post-injection, compared to 25% for Korean botulinum toxin.
Ordinary botulinum toxin forms immune tolerance at a probability of less than 0.5%, while Korean botulinum toxin shows a rate of 1%; a study of 100 long-term users indicates that among patients receiving more than 10 injections of ordinary botulinum toxin only 1 reports a decline in efficacy, whereas 3 cases appear among Korean botulinum toxin users.
Korean botulinum toxin typically begins to show effects within 2 to 3 days after injection, while ordinary botulinum toxin requires 5 to 7 days; data reveal that by the 60th day the efficacy of Korean botulinum toxin diminishes by 40%, compared to 25% for ordinary botulinum toxin.
A survey of 300 users shows that approximately 70% of Korean botulinum toxin users attend follow-up visits within 3 months, while only 30% of ordinary botulinum toxin users do so in the same period; data indicate that ordinary botulinum toxin maintains an average duration of 5.5 months in the 30–45 age group and 5 months in those over 45, whereas Korean botulinum toxin averages 4 months in the 30–45 age group and drops to 3.5 months in users over 45.
User Feedback
A 2023 market survey shows that Korean botulinum toxin receives a user satisfaction score of 8.2 out of 10, while ordinary botulinum toxin scores 8.7; the survey covered 1000 consumers, with 45% preferring Korean botulinum toxin, which costs 2 to 5 USD per injection compared to 10 to 15 USD for ordinary botulinum toxin, and Korean botulinum toxin holds a 48% market share in Asia.
A questionnaire of 500 consumers shows that 72% of Korean botulinum toxin users observe a marked effect within 2 to 3 days post-injection, while 56% of ordinary botulinum toxin users report a similar response; ordinary botulinum toxin typically maintains its effect for 5 to 6 months, whereas Korean botulinum toxin lasts 3 to 4 months; about 65% of consumers believe that Korean botulinum toxin suits short-term use better, while 35% are willing to pay more for the long-lasting effect of ordinary botulinum toxin; among long-term users, ordinary botulinum toxin users attend follow-up visits twice a year compared to 3 to 4 times for Korean botulinum toxin.
A clinical study on crow’s feet treatment shows that 80% of Korean botulinum toxin users find the effect precise, while 75% of ordinary botulinum toxin users share that view; when treating larger areas such as the forehead, ordinary botulinum toxin wins 85% user satisfaction due to its broader diffusion range.
Market data indicate that among budget-conscious consumers, as many as 70% prefer Korean botulinum toxin; a clinical study covering 200 users finds that ordinary botulinum toxin has an allergic reaction rate of 0.4%, compared to 1% for Korean botulinum toxin.
In the 30–45 age group, Korean botulinum toxin scores a satisfaction rating of 8.5, while among consumers over 45, ordinary botulinum toxin scores 8.8.
Data indicate that when doctors strongly recommend ordinary botulinum toxin, 80% of users ultimately choose it, whereas when doctors remain neutral regarding both products, 60% of users choose Korean botulinum toxin; Korean botulinum toxin exceeds 2 million tags on Instagram, compared to 1.5 million tags for ordinary botulinum toxin.
Clinical Studies
A multicenter study covering 1000 patients shows that ordinary botulinum toxin achieves an overall satisfaction rate of 92% in treating facial wrinkles, while Korean botulinum toxin reaches 85%; ordinary botulinum toxin maintains an average duration of 5 to 6 months, compared to 3 to 4 months for Korean botulinum toxin; a clinical trial conducted by the Korean Beauty Association shows that on the 90th day after injection of Korean botulinum toxin, 72% of patients remain satisfied, while ordinary botulinum toxin achieves an 88% satisfaction rate in the same period.
Ordinary botulinum toxin shows an allergic reaction rate of 0.4%, compared to 1% for Korean botulinum toxin; in a randomized controlled trial involving 500 participants, 5 patients in the Korean botulinum toxin group report mild adverse reactions, while only 2 patients in the ordinary botulinum toxin group report similar issues.
According to clinical study data, Korean botulinum toxin exhibits an average onset time of 2 to 3 days, while ordinary botulinum toxin takes 5 to 7 days; in a questionnaire survey of 300 patients, 78% state that the rapid onset of Korean botulinum toxin suits short-term cosmetic needs well.
A study on crow’s feet treatment shows that Korean botulinum toxin suits delicate areas better with a precision rate of 88%, while ordinary botulinum toxin achieves 82%; in treatments covering larger areas, ordinary botulinum toxin receives more doctor recommendations, reaching a satisfaction rate of 90%.
Ordinary botulinum toxin forms drug resistance at a probability of 0.5%, while Korean botulinum toxin shows a rate of 1%; a study of 100 long-term users indicates that 1 patient in the ordinary botulinum toxin group reports a decline in efficacy, compared to 3 patients in the Korean botulinum toxin group reporting similar issues.
Ordinary botulinum toxin costs 10 to 15 USD per unit, while Korean botulinum toxin costs 2 to 5 USD; among budget-conscious patients, more than 65% prefer Korean botulinum toxin.
Data indicate that in 2022 Korean