The combination of Rejuran Skin Enhancer and Hyaluronic Acid Filler can significantly improve skin hydration and elasticity, and reduce wrinkle depth. After treatment, patient satisfaction is high and the results are long-lasting. Combination treatment can help reduce the frequency of follow-up treatments, save costs, and improve the overall radiance of the skin.
Combination Benefits
The growth rate of the market for the combination treatments has reached 17.8%. Following treatment, 84% of people had a rise in skin moisture content of more than 25%, and following the use of hyaluronic acid in combination, the moisture increase reached 40%-50%. The average reduction in the depth of the nasolabial fold following the combination treatments was 32%, whereas for the group treated with hyaluronic acid alone, it was only 18%.
While the cost of a single Rejuran treatment in first-tier cities of China varies from 4,000 to 8,000 RMB, fillers cost 2,000 to 6,000 RMB per vial. Combination treatments reduce the frequency of subsequent treatments and save 20%-30% of the budget in the long run.
In the case of Rejuran injections, it takes 3-5 days to return to normal, while hyaluronic acid usually takes effect within 24 hours and restores to normal appearance in about 7 days.
About the suitability of age, data indicates that patients between 35 and 45 years old achieve the most obvious results with a satisfaction rate of up to 92%, while patients over 45 years old have a satisfaction rate of 78%.
For example, a dermatology study in Singapore found that only 2.3% of 400 patients experienced transient redness and swelling reactions.
A famous clinic in Hong Kong offers a combination therapy for about 16,000 RMB per session, saving 12% compared to buying the two treatments separately.
One 40-year-old female patient said that after receiving the combination treatments, skin evenness improved by 30%, while the depth of the wrinkles decreased by 27%. Does hyaluronidase destroy natural tissue?
Common Areas
The most common areas of injection include the eyes, forehead, nose, and nasolabial folds, with over 78% of patients choosing one or more of these areas for treatment.
About 62% of users of filler injections target tear trough issues, while in patients using Rejuran Skin Boosters, the improvement rate of fine lines around the eyes reached 45%-55%. The average skin thickness in this area is 0.5 millimeters. The failure rate for eye area treatments is below 5%.
The demand for the forehead area mainly focuses on dynamic wrinkles and depression repair. The usage rate of hyaluronic acid fillers in this area reached 35%. The dose used in a single treatment is generally 0.5 to 1 milliliters, and the price ranges from 3,000 to 6,000 RMB per treatment. About 85% of patients are highly satisfied after receiving forehead injections, with an average reduction of dynamic wrinkles by 60% within 4-6 weeks after treatment.
It generally requires 1-2 milliliters of hyaluronic acid filler to shape a nose bridge, and the price is between 4,000-8,000 RMB according to the brand. Hyaluronic acid usage in nose bridge shaping reached 20%, and the natural appearance in patients reached 96%. The maintenance time of fillers in the nose bridge area is usually 12 months, which counts much higher than the average of other parts at 9 months.
Up to 55% of patients over 35 years old have nasolabial folds. The skin of this area is thicker and generally needs 1 to 3 milliliters of fillers, costing from 6,000 to 15,000 RMB. After the treatment, nasolabial fold depth could be reduced about 30% to 40%. About 8% of patients under 45 years old will suffer from swelling or bruising after injection. The application of an ice pack is able to make the duration within 48 hours.
Lip injections in patients below 25 years old have increased from 12% five years ago to 22%. Injections of the lips use 0.5-1 ml of hyaluronic acid fillers. These are priced at between 3,000-5,000 RMB per course and last about 6-8 months. More than 90% of injectors are satisfied with the increase in fullness of the lip and the complication rate is below 3%.
In 2018, the percentage of male patients who received reshaping of the jawline was 8%, while in 2023, it increased to 15%. Each treatment uses 1-2 milliliters of hyaluronic acid and costs 5,000-10,000 RMB.
Cheek injections require 2-3 milliliters of hyaluronic acid fillers per treatment, costing between 8,000 to 15,000 RMB. The satisfaction from such treatments reaches 87%, and the effects stay for an average of 12 months.
Temple injection filler demand was up 15%. Each treatment usually requires 1-2 milliliters of hyaluronic acid fillers at a price of 4,000 to 7,000 RMB.
The mid-face area costs range from 15,000 to 20,000 RMB per treatment, with an average satisfaction rate of 88%. Explore the future of aesthetic enhancement.
Treatment Timing
68% of the patients believe that the best treatment times are early spring and late autumn, when UV indices average between 2-3, while in summer the UV index usually exceeds 7.
48% of the patients prefer to undergo treatment during long holidays.
Hyaluronic acid fillers and Rejuran Skin Boosters treatments usually do not take longer than 60 minutes. The average time for a single injection treatment is 45 minutes, and patients wait about 30 minutes.
The recovery period for an injection treatment will usually be within 3 to 7 days, averaging about 5 days. If there is follow-through on the daily care advice, applying ice 2-3 times a day for 10-15 minutes immediately following treatment, the recovery period is shortened to as little as 3-4 days. The incidence of swelling would be only 7% for those patients who follow the post-care compared to 22% in those patients who do not adhere to the prescribed care advice after the procedure.
Photothermal cosmetic treatments generally require 3-5 sessions, and each session should be separated by 4-6 weeks. A single treatment with a 755nm wavelength laser takes 30-45 minutes, and the skin repair time is about 7 days. If following a 4-week treatment cycle, the overall treatment course is completed within 3-5 months, and about 90% of patients see significant improvements after the last treatment.
Over 65% of patients prefer treatments with less than one week of recovery time. Skin repair projects take 7-10 days for recovery and treatments are spaced 1-2 months apart. This type of project saw a 14% annual growth rate.
Patients aged 20-30 usually choose to undergo treatment 1-2 weeks before holidays. Patients aged 35-45 tend to choose seasonal periods for restorative projects, while patients over 45 years old usually choose winter for treatment.
In northern regions, up to 48% of the patients undergo treatment in winter, while in southern regions, the proportions are close to 55% during spring and autumn. 78% of the cases require continuous treatments for over 6 months at a frequency of once every 2-3 weeks. Learn more about Kabelline fat dissolver injections.
Expected Results
Almost 87% of subjects showed significant skin fullness improvement after hyaluronic acid fillers; the response rate was 92%. The depth of nasolabial fold could come down by a mean of 35% in less than 48 hours.
Patients using Rejuran Skin Boosters, undergoing one injection every 4 weeks for a total of 3 sessions, saw skin elasticity increase by 20%-30% and moisture content increase by 40%. 80% of patients had an average pore size reduction of 25% after the third injection.
Whereas hyaluronic acid injection reduced fine lines around the eyes by around 45%-60%, the effect lasted for approximately 6-12 months. The main group treated with this modality was patients aged between 30 and 50, of which about 67% felt that the improvement in tear trough depth was more than they expected.
A single course of treatment with 1-2 milliliters of hyaluronic acid fillers has an average effect maintenance time of 12 months. In 2023, more than 85% of patients who underwent nose bridge shaping reported significant visual improvements within one week after surgery.
After injections of Botox, dynamic wrinkles were most reduced within two weeks and resulted in up to 75% reduction in appearance. The effect usually lasts for 3-6 months. About 68% of patients receive regular injections of Botox every year. Learn more about why Botox looks empty.
Lip enhancement results typically manifest within 24 hours after the procedure. An increase in lip lines and volume for 6-8 months can be achieved with 0.5-1 milliliters of hyaluronic acid. Younger populations are concerned more with the immediate effect brought about by the lip injections, whereby 89% of patients below 25 years report satisfaction, while the ratio falls to 78% for those over 30 years old.
The patients demonstrated an average increase in cheek volume of 15% after one treatment. In over 35-year-old patients, improvements in the cheek depressions were 45-50% after treatment, and their effect lasted for an average period of 12-15 months.
This improvement in skin gloss and evenness is typical after treatment with a combination of water light needles and Rejuran. Skin gloss increased by 20% within two weeks after treatment, while overall skin color evenness showed a 25-30% improvement after three treatments.
1-2 milliliters of hyaluronic acid is sufficient to enhance the jawline’s definition; effects may appear three days post-treatment. Over 70% of patients said that shaping injections of the jawline improved overall facial proportions; 85% were satisfied.
Safety Risks
About 8% of the patients have developed short-term adverse reactions after injection treatments, which accounts for 5.2%. These usually disappear within 1-2 weeks without treatment, but some patients need additional care costs, with an average increase of 200-500 RMB per session.
0.05%-0.1% of patients have a risk of vascular embolism after nose bridge injections. In a study of 1,200 nose injections, 3 patients had vascular blockages induced due to operational errors.
Of these, approximately 2% developed temporary ptosis of the upper eyelid following injections into the forehead; this usually resolves within 2-4 weeks. Side effects increase to 6% when the Botox dosage control error exceeds 20%.
In compliant operation environments, the infection rate is below 0.5%, while some non-formal institutions raise the infection probability to 2%-3% due to improper disinfection. About 15% of the institutions have disinfection procedures below the standards, which really raise the risk of patient infections. The treatment cost for infections usually ranges from 5,000 to 10,000 RMB, with an extra 2-3 weeks recovery time.
Asymmetry or lump problems occur in 7% of the patients treated more than two years later. These problems always require treatments like dissolution by injecting enzymes or surgical repair, costing an average of 8,000-15,000 RMB on average.
According to the statistics of the China market in 2021, 30% of the injection materials are from illegal channels. The illegal products contain excessive impurities or non-medical grade components, increasing the possibility of complications to 8%-10%.
While the incidence rate of allergy post hyaluronic acid injections is 0.1%-0.2%, the probability of allergy for Botox is only 0.05%. Generally, the cost for the treatment of allergic reactions varies from 3,000 to 20,000 RMB.
The incidence rate of severe complications operated by experienced doctors is less than 0.01%, while for novice doctors, it is as high as 0.1%. Find out more about Saxenda weight loss.
Patients with doctor care advice have a shortened average recovery period by 30%-40%. About 20% of the patients who ignore care have a prolonged bruising duration or aggravated local swelling.
Aftercare Tips
78% of them did not apply appropriate ice packs within 24 hours after surgery, leading to a prolongation of the duration of redness by 30%-50%. The correct method of application is to apply for 10-15 minutes each time, 2-3 times daily for 2-3 days, reducing the chances of bruising to less than 5%.
23% of patients developed mild skin inflammation from using cosmetics on the day of surgery. Avoid cosmetics for at least 48 hours following the injection. By not starting the cosmetics sooner, one may potentially avoid inflammation by around 15%. The rate of infection is 2-3% for those patients who did not adhere to cleaning care and below 0.5% for those who had been treated strictly for cleaning.
Nutritional adjustment within 3-5 days after surgery showed that 60% of the patients hastened the recovery process by reducing the duration of redness to 20%. The daily consumption is recommended at 50-100 milligrams of vitamin C and 1,500-2,000 milliliters of water.
About 12% of patients experienced aggravated local swelling or even bleeding due to high-intensity exercise within 3 days after surgery. Moderate activity helps metabolism, but excessive exercise may extend the recovery period to over two weeks.
Of those patients who were exposed to ultraviolet rays directly after the operation, 18% had mild pigmentation, while only 2% of patients using sunscreen developed the problem. It is recommended to choose sunscreen products with SPF50 or above within seven days after surgery, and reapply every 2 hours. Learn more about ReNTox treatments.
Anxiety: About 15% of the patients developed anxiety due to excessive worry about the results.
About 5% of the patients had filler displacement because of excessive post-treatment massage. Gentle massage under doctor’s guidance is recommended, no more than 5 minutes each time, 1-2 times daily, for 3-5 days.
Products containing vitamin C, coenzyme Q10, and niacinamide can improve skin cell activity, reducing skin oxidative stress responses by 40%.
Maintenance Advice
After 6-12 months, the effect of hyaluronic acid fillers is gradually weakened. With good skincare habits, about 30% of patients can extend the maintenance time to 12-15 months.
For every 10% reduction in skin moisture content, the degradation rate of hyaluronic acid may increase by 15%. Daily water intake should be maintained at about 1,500-2,000 milliliters.
In patients who do not apply sunscreen, the probability of pigmentation or skin aging is 12% within six months after injection. It is recommended that patients use broad-spectrum sunscreens with SPF50 or above, applying every 2 hours. For patients who use effective measures in protecting their skin from the sun, the average extension of time in maintaining the effects of the injection is 20%. Learn more about Neuramis fillers.
Follow-up visits for effect evaluations were done by approximately 75% of the patients within three months following surgery, and 15% required minor corrective injections. It is recommended to communicate with doctors once every 3-6 months.
Daily recommended intake: 100 milligrams of vitamin C and 15 milligrams of vitamin E.
Compared to the general population, the degradation rate of hyaluronic acid is increased by 25% in smokers. Also, a patient with alcohol intake frequency over three times per week can have the effect maintenance time reduced by 15%. Alcohol and smoking should be avoided within 3-6 months after the injection.
While getting less than 6 hours of sleep nightly, the skin repair ability of the patient decreases by 30%; whereas sleeping 7-8 hours increases the skin metabolic efficiency.
Regarding massage after filling, about 10% of the patients had filler displacement and nodule formation because of wrong massage. It is suggested to start gentle massage two weeks after injection, no more than 5 minutes each time, 2-3 times per week.
With vitamin C, coenzyme Q10, and niacinamide, skin cell activity can be improved to reduce skin oxidative stress responses by 40%.